Serum Proteome Alterations in Human Cystathionine β-Synthase Deficiency and Ischemic Stroke Subtypes

Serum 25-Hydroxyvitamin D Deficiency in Ischemic Stroke and Subtypes in Indian Patients

BACKGROUND AND PURPOSE Vitamin D deficiency is common across all age groups and may contribute to cardiovascular diseases. Serum 25-hydroxyvitamin D deficiency causing ischemic stroke has been documented in recent reports. AIM To investigate the association of serum 25-hydroxyvitamin D deficiency with ischemic stroke and subtypes. METHODS We recruited 250 consecutive ischemic stroke patient...

Homocystinuria due to cystathionine beta synthase deficiency.

A two year-old male child presented with cutis marmorata congenita universalis, brittle hair, mild mental retardation, and finger spasms. Biochemical findings include increased levels of homocysteine in the blood-106.62 micromol/L (normal levels: 5.90-16 micromol/L). Biochemical tests such as the silver nitroprusside and nitroprusside tests were positive suggesting homocystinuria. The patient w...

Homocystinuria due to cystathionine synthase deficiency.

Genetic background in apolipoprotein A - I and cystathionine β - synthase deficiency

1. Abstract 2. Introduction 3. Material and Methods 3.1. Animals 3.2. PCR Genotyping 3.3. Plasma determinations 3.4. Blood pressure 3.5. Histological analysis 3.6. RNA isolation, Affymetrix oligonucleotide array hybridization, and data analysis 3.7. Statistical analysis 4. Results 4.1. Plasma biochemistry 4.2. Arterial blood pressure 4.3. Plasma NO levels 4.4. Histological analyses of aorta 4.5...

Retinopathy in ischemic stroke subtypes.

BACKGROUND AND PURPOSE Lacunar stroke is associated with an intrinsic cerebral small vessel disorder of unknown etiology, although possible causes include increased blood-brain barrier permeability. Retinal arterioles are similar to cerebral small vessels and retinopathy occurs secondary to increased blood-retinal barrier permeability. We hypothesized that there would be higher rates of retinop...